DLC1 (deleted in liver cancer) is a Rho GTPase-activating protein actively involved in the regulation of cell proliferation, modulation of cytoskeletal dynamics ...
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The gene transfer resulted in the inhibition of cell proliferation and increase in sub-G1 population. Forced expression of DLC1 also inhibited cell migration ...
CircDLC1 is derived from 14th, 15th, and 16th exons of DLC1 gene. CircDLC1 interacted with RNA-binding protein HuR (shown in Fig. 10.1). HuR is involved in the ...
In basal condition, AMBRA1 interacts with BECN1/BECLIN 1 (beclin 1, autophagy related) and PIK3C3/VPS34 (phosphatidylinositol 3-kinase catalytic subunit type 3) ...
Mutations in numerous proto-oncogenes and tumor suppressor genes, such as p53, p73, Rb, APC, DLC-1, DLC-2, PTEN, SOCS1, GSTP1, HCCS1, Smad2/4, AXIN1, IGF-2, β- ...
Membrane-Associated Guanylate Kinases: CASK and DLG3 ... Calmodulin-associated serine kinase (Cask) is a protein belonging to the MAGUK family. It was initially ...
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The mutational spectrum depends very largely on the DNA sequence characteristics of the gene in question (e.g., the presence of repeat units or homologous ...
DLC-1 (deleted in liver cancer 1) is a candidate tumor suppressor gene for hepatocellular carcinoma and other cancers. It is the human homologue of rat p122 ...
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