DLC1 (deleted in liver cancer) is a Rho GTPase-activating protein actively involved in the regulation of cell proliferation, modulation of cytoskeletal dynamics ...
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The gene transfer resulted in the inhibition of cell proliferation and increase in sub-G1 population. Forced expression of DLC1 also inhibited cell migration ...
CircDLC1 is derived from 14th, 15th, and 16th exons of DLC1 gene. CircDLC1 interacted with RNA-binding protein HuR (shown in Fig. 10.1). HuR is involved in the ...
In basal condition, AMBRA1 interacts with BECN1/BECLIN 1 (beclin 1, autophagy related) and PIK3C3/VPS34 (phosphatidylinositol 3-kinase catalytic subunit type 3) ...
Mutations in numerous proto-oncogenes and tumor suppressor genes, such as p53, p73, Rb, APC, DLC-1, DLC-2, PTEN, SOCS1, GSTP1, HCCS1, Smad2/4, AXIN1, IGF-2, β- ...
Membrane-Associated Guanylate Kinases: CASK and DLG3 ... Calmodulin-associated serine kinase (Cask) is a protein belonging to the MAGUK family. It was initially ...
The mutational spectrum depends very largely on the DNA sequence characteristics of the gene in question (e.g., the presence of repeat units or homologous ...
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DLC-1 (deleted in liver cancer 1) is a candidate tumor suppressor gene for hepatocellular carcinoma and other cancers. It is the human homologue of rat p122 ...
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